KMID : 0615720030200020123
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Jouranl of Korean Acupuncture and Moxibustion society 2003 Volume.20 No. 2 p.123 ~ p.134
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The Effects of electroacupuncture stimuli to the Doublecortin and PSA-NCAM positive cells in the Dentate Gyrus of spontaneously hypertensive rats
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Abstract
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Objective : This experimental in vitro study investigates the effects of electro acupuncture stimuli to the DCX and PSA-NCAM positive cells in the dentate gyrus of spontaneously hypertensive rats.
Methods : We used immunohistochemical methods to observe the change of neuron cells, and then counts the immunoactive cells under the 100¡¿visual field optical microscope.
Results :
1. The counts of DCX-positive cells in the dentate gyrus significantly increased in the 2Hz group versus control group. Otherwise 100Hz group did not have a significant differance.
2. The counts of PSA-NCAM-positive cells in the dentate gyrus rather decreased in the both 2Hz group and 100Hz versus control group.
Conclusions : We find out the electro acupuncture stimuli have some effects upon cerebral neuron cell in the dentate gyrus spontaneously hypertensive rats.
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